Glutaric anhydride

  • 2H-Pyran-2,6(3H)-dione, dihydro
  • Glutaric acid anhydride
  • Pyroglutaric acid
  • Pentanedioic acid anhydride
  • Pentanedioic anhydride
Formula
C5H6O3
Structure
Description
White powder.

Registry Numbers and Inventories.
CAS
108-55-4
EC (EINECS/ELINCS)
203-593-6
EC Class
harmful, irritant
R 21/22 37/38 41
S 26 36/37/39
RTECS
MA3850000
RTECS class
Other
Beilstein/Gmelin
110051
Beilstein Reference
5-17-11-00009
Swiss Giftliste 1
G-2259
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C5H6O3
Formula mass
114.10
Melting point, °C
52 - 55
Boiling point, °C
287
Vapor pressure, mmHg
0.003 (25 C)
Density
1.411 g/cm3
Solubility in water
Very soluble
Partition coefficient, pKow
-0.92
Heat of vaporization
52.6
Heat of combustion
-2207 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.
Disposal code
4
Stability
May decompose on exposure to moist air or water.
Incompatibilities
Strong oxidizing agents, acids, bases, alcohols, amines.
Decomposition
Carbon monoxide, carbon dioxide, acrid smoke and fumes.

Fire.
Flash Point,°C
120
Autoignition, °C
320
Upper exp. limit, %
13.1
Lower exp. limit, %
2
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Do NOT use water directly on fire. Use foam, dry chemical, or carbon dioxide.

Health.
Poison_Class
4
Exposure effects
   Ingestion
May cause central nervous system depression. May cause gastrointestinal tract damage. May be harmful if swallowed.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes skin irritation. If absorbed, may cause symptoms similar to those for ingestion. May be harmful if absorbed through the skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
11 Organic anhydrides
HS Code
2917 19 90