Glycine

  • Aminoacetic acid
Formula
H2NCH2COOH
Structure
Description
White crystals.
Uses
Biologically significant amino acid.

Registry Numbers and Inventories.
CAS
56-40-6
EC (EINECS/ELINCS)
200-272-2
S 22 24/25
RTECS
MB7600000
RTECS class
Mutagen
Merck
13,4504
Beilstein/Gmelin
635782
Beilstein Reference
4-11-00-00122
Swiss Giftliste 1
G-6986
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H5NO2
Formula mass
75.07
Melting point, °C
83
Boiling point, °C
181
Decomposition point, °C
232 - 236
Vapor pressure, mmHg
0.012
Critical temperature
387
Critical pressure
61.8
Density
1.64 g/cm3
Solubility in water
250 g/L
pKa/pKb
2.37 (pKa)
Partition coefficient, pKow
-1.03
Heat of combustion
-974.1 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia.

Fire.
Flash Point,°C
99.5
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Hazards
LOW. Ignites at very high temperatures.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
-
Exposure effects
mental status changes, cerebral edema, seizures, and coma have been reported following systemic absorption of glycine irrigation solutions. Acute exposure - neurologic: mental status changes, cerebral edema, seizures, and coma have been reported following systemic absorption of glycine irrigation solutions.
   Ingestion
Ingestion of large amounts may cause gastrointestinal irritation. Low hazard for usual industrial handling.
   Inhalation
Low hazard for usual industrial handling.
   Skin
Low hazard for usual industrial handling. May be absorbed through the skin.
   Eyes
Dust can cause eye irritation. Symptoms include stinging, tearing, redness, and swelling of eyes.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2922 49 10