Glyoxylic acid

  • Formylformic acid
  • alpha-Ketoacetic acid
  • Oxoacetic acid
  • Oxalaldehydic acid
  • Oxoethanoic acid
Formula
OHCCOOH
Structure
Description
Supplied as a 50% aqueous solution. Colorless to straw yellow.
Uses
Intermediate for flavorings, perfumes, pharmaceuticals, dyes, plastics, agricultural chemicals.

Registry Numbers and Inventories.
CAS
298-12-4
EC (EINECS/ELINCS)
206-058-5
R 34 41
S 26 36/37/39 45
RTECS
MD4550000
RTECS class
Mutagen
UN (DOT)
3265
Merck
13,4524
Beilstein/Gmelin
741891
Beilstein Reference
4-03-00-01489
Swiss Giftliste 1
G-5990
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H2O3
Formula mass
74.04
Melting point, °C
97 - 98
Boiling point, °C
225
Vapor pressure, mmHg
0.033 (25 C)
Vapor density (air=1)
>1
Density
1.342 g/cm3 (20 C)
Solubility in water
Very soluble
Refractive index
1.41 (20 C)
pKa/pKb
2.61 (pKa)
Partition coefficient, pKow
-0.93
Heat of vaporization
50.8 kJ/mol
Heat of combustion
-525 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Neutralizing Agents for Acids and Caustics: Lime.
Stability
Forms a syrup on short exposure to air hemihydrate.
Incompatibilities
Reacts in this way with all bases, both organic (for example, the amines) and inorganic Can react with active metals to form gaseous hydrogen and a metal salt Flammable and/or toxic gases and heat are generated by the reaction with with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.

Fire.
Flash Point,°C
104
Fire fighting
Fire Extinguishing Agents Not to Be Used: Avoid direct contact between water and acid.Fire Extinguishing Agents: Dry chemical, carbon dioxide or water spray.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
2
Exposure effects
Increased deep tendon reflexes, drowsiness, stupor, seizures and coma may be noted.
   Ingestion
Persistent vomiting, hematemesis and hemorrhagic gastritis due to the corrosive action of oxalic acid on the mucous membranes may occur immediately following ingestion.
   Inhalation
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.
   Skin
Dermal exposure may result in corrosive action on the skin. Skin lesions begin with epithelial cracking and the formation of slow-healing ulcers.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Remove to fresh air. If breathing is difficult, give oxygen.
   Skin
Remove contaminated clothing and shoes. Flush with water.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
3265
Response guide
Hazard class
8
Packing Group
I; II; III
 
USCG CHRIS Code
GAC
 
IMO Chemical Code
17
IMO Pollution Category
D
IMO Hazard code
S