Glyphosate

  • N-(Phosphonomethyl)glycine
Formula
C3H8NO5P
Structure
Description
Odorless white powder.
Uses
Non-selective, non-residual post-emergence herbicide.

Registry Numbers and Inventories.
CAS
1071-83-6
EC (EINECS/ELINCS)
213-997-4
EC Index Number
607-315-00-8
EC Class
Irritant; Dangerous for the Environment
RTECS
MC1075000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Human Data
Merck
12,4522
Beilstein/Gmelin
2045054
EPA OPP
471300
Swiss Giftliste 1
G-42684
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H8NO5P
Formula mass
169.07
Melting point, °C
230
Decomposition point, °C
230
Density
1.74 g/cm3 (20 C)
Solubility in water
12 g/L
Partition coefficient, pKow
-0.45

Hazards and Protection.
Storage
Contact of the saltsolution with galvanized metal causes loss of activity. Store in synthetic containers. Mix, store, and apply glyphosate solutions in stainless steel, aluminum, fiberglass, plastic or plastic-lined containers.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Small spills/leaks
If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
May react with galvanized steel or unlined steel (except stainless steel) containers to produce hydrogen gas which may form a highly combustible or explosive gas mixture It
Decomposition
When heated to decomposition it emits very toxic fumes of oxides of nitrogen and oxides of phosphrous.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.
Fire potential
This material is probably combustible.

Health.
Poison_Class
4
Exposure effects
Mental status changes may be seen late in the course of glyphosate poisoning.
   Ingestion
Common signs - nausea and vomiting; erythema of mucous membranes; epigastric pain.
   Inhalation
Life-threatening effects include pulmonary edema and aspiration pneumonitis. Irritation occurs.
   Skin
Commercial glyphosate formulations have caused erythema, piloerection, and contact dermatitis.
   Eyes
Irritation of the mouth and throat is possible after ingestion. Inflammation of the eye may occur following splash contact; nystagmus rarely occurs with systemic poisoning.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.