Gossypol

  • 2,2'-Bis(1,6,7-trihydroxy-3-methyl-5-isopropyl-8-aldehydonaphthalene)
  • 8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methyl-2,2'-bisnaphthalene
Formula
C30H30O8
Structure
Description
Solid.
Uses
Male antifertility agent.

Registry Numbers and Inventories.
CAS
303-45-7
RTECS
DU3100000
RTECS class
Mutagen; Reproductive Effector; Human Data; Natural Product
Beilstein/Gmelin
1917878
Beilstein Reference
4-08-00-03754
New Zealand
Listed

Properties.
Formula
C30H30O8
Formula mass
518.56
Decomposition point, °C
189
Vapor pressure, mmHg
1E-20 (25 C)
Density
1.17 g/cm3
Solubility in water
Insoluble
pKa/pKb
7.15 (pKa)
Heat of vaporization
107.2 kJ/mol

Hazards and Protection.
Storage
Store at 2-8 C.
Protection
Wear respirator, chemical safety goggles, rubber boots and rubber gloves.
Small spills/leaks
Sweep up and place in a bag for laterr waste disposal. Avoid raising dust. Wash spill site after material pickup.
Stability
Stable at normal temperatures and pressures.

Fire.
Fire fighting
Wear self-contained breathing apparatus and protective coloting to prevent contact with skin and eyes. Extinguish using water spray.

Health.
Exposure effects
Targets male reproductive system first.
   Ingestion
May be irritating to the gastrointestinal tract.
   Inhalation
Edema of the lungs, shortness of breath and paralysis.

First aid
 
   Ingestion
Wash mouth out with water provided the person is concious.
   Inhalation
Move to fresh air and seek medical assistance.
   Skin
Flush with copous amounts of water for at least 15 minutes.
   Eyes
Flush with copous amounts of water for at least 15 minutes while separating the eyelids. Seek medical assistance.

Transport.