Guanidine hydrochloride

  • Guanidinium chloride
  • Guanidine, monohydrochloride
Formula
H2NC(NH)NH2.HCl
Structure
Description
White crystals crystalline powder.

Registry Numbers and Inventories.
CAS
50-01-1
EC (EINECS/ELINCS)
200-002-3
EC Index Number
607-148-00-0
EC Class
Harmful; Irritant
R 22 36/38
RTECS
MF4300000
RTECS class
Mutagen; Primary Irritant
Merck
13,4578
Beilstein/Gmelin
3591990
Beilstein Reference
4-03-00-00148
Swiss Giftliste 1
G-5197
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
CH6ClN3
Formula mass
95.54
Melting point, °C
185
Density
1.354 g/cm3
Solubility in water
2150 g/L (20 C)

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Carefully scoop up and place into appropriate disposal container. Provide ventilation. Clean up residual material by washing area with a 2-5% solution of soda ash.
Disposal code
3
Stability
Stable under normal shipping and handling conditions. However, may decompose if heated.
Incompatibilities
Strong oxidizing agents, moisture.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use water spray, dry chemical, or carbon dioxide. Use agent most appropriate to extinguish fire.
Health
2
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Repeated or prolonged exposure may cause CNS stimulation.
   Ingestion
Harmful if swallowed. May cause irritation of the digestive tract. May cause minor neurological effects.
   Inhalation
Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2925 20 00