Halcinonide

  • Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-beta,16-alpha,17-trihydroxy, cyclic-16,17-acetal with acetone
Formula
C24H32ClFO5
Structure
Uses
A topical steroid. Used to treat inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis.

Registry Numbers and Inventories.
CAS
3093-35-4
EC (EINECS/ELINCS)
221-439-6
RTECS
TU5010200
RTECS class
Drug; Mutagen
Merck
12,4621
Beilstein/Gmelin
1358242
Beilstein Reference
5-19-06-00301
Canada DSL/NDSL
DSL

Properties.
Formula
C24H32ClFO5
Formula mass
454.97
Solubility in water
4E-15 (25 C)
pKa/pKb
13.25 (pKa)
Heat of vaporization
97.4 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
295
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful. Possible risk of harm to the unborn child.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.