Hexachlorocyclohexane (mixed isomers)

  • 1,2,3,4,5,6-Hexachlorocyclohexane (mixed isomers)
  • BHC/HCH (mixture of isomers)
  • 1,2,3,4,5,6-Benzenehexachloride (mixed isomers)
Formula
C6H6Cl6
Structure
Description
White to yellow powder or flakes. Musty odor.
Uses
Control of leafhoppers, stem borers, etc, in lowland rice. Kotol liq seed treatment for reduction of wireworm damage in winter & spring sown cereals. Lindocol for control of pests of cereals, sugar beets & oilseed rape. Former use.

Registry Numbers and Inventories.
CAS
608-73-1
EC (EINECS/ELINCS)
210-168-9
RTECS
GV3150000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data
UN (DOT)
2761
Beilstein/Gmelin
1907331
Beilstein Reference
2-05-00-00011
EPA OPP
8901
Swiss Giftliste 1
G-1257
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H6Cl6
Formula mass
290.82
Melting point, °C
113
Vapor density (air=1)
1.85
Density
1.87 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.52299 (124 C)

Hazards and Protection.
Storage
Storage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Dispensers of liquid detergent should be available. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, and disposable plastic aprons might provide additional protection. Protective clothing should be of distinctive color, as a reminder not to be worn outside the laboratory.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Stable to light, heat, air, carbon dioxide and strong acids.
Incompatibilities
Incompatible with strong oxidizing and reducing agents Incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Decomposition
When heated to decomposition it emits highly toxic fumes of phosgene and hydrogen chloride.

Fire.
Fire fighting
Use method most appropriate to fight surrounding fire.
Fire potential
Not flammable.
Combustion products
Toxic gases are generated when solid is heated or when soln burns.

Health.
Exposure limit(s)
TLV (as gamma-isomer): ppm; 0.5 mg/m3 (skin) (ACGIH 1991-1992).
Carcinogin
I-2B, N-2, CP65
Poison_Class
3
Exposure effects
Elevated body temperature and respiratory depression may occur with prolonged seizures. Abnormally low blood pressure may occur with severe poisoning. Central nervous system excitation, agitation, nervousness, tremor, seizures, sensory disturbances, and peripheral neuropathy may occur. Lindane did not have reproductive effects in a 3-generation rat study. It has not been teratogenic in animals. It disturbed the estrus cycle and reduced fertility in female rats. It has been detected in human breast milk. It produced degenerative changes in the testes of rats.
   Ingestion
Nausea, vomiting, diarrhea, hypersalivation, and pancreatitis may occur following ingestion.
   Inhalation
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.
   Skin
Extensive contact may result in dermatitis, irritation, and local hypersensitivity.
   Eyes
Lindane can irritate the eyes, nose, and throat.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove all exposed clothing and jewelry taking necessary precautions to prevent secondary exposure to health care providers. Irrigate exposed areas promptly with copious amounts of water for at least 30 minutes. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Carefully observe patient for development of clinical signs and symptoms, and administer treatment as described in dermal exposure where appropriate.

Transport.
UN number
2761
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
CLF
 
36 Halogenated hydrocarbons