Hexadecyltrimethylammonium chloride

  • 1-Hexadecanaminium
  • Cetrimonium chloride
  • Hexadecan-1-aminium
  • N,N,N-Trimethyl-1-hexadecanaminium chloride
  • Trimethylhexadecylammonium chloride
Formula
C19H42N.Cl
Structure
Description
Colorless to pale yellow liquid with an odor of rubbing alcohol.
Uses
Used in antifungal formulation, in hair conditioner formulation, disinfectant, cationic detergent.

Registry Numbers and Inventories.
CAS
112-02-7
EC (EINECS/ELINCS)
203-928-6
RTECS
ML9145000
RTECS class
Mutagen
UN (DOT)
1759
Beilstein/Gmelin
3657974
Beilstein Reference
4-04-00-00819
EPA OPP
69133
Swiss Giftliste 1
G-7074
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C19H42N*Cl
Formula mass
320.07
Melting point, °C
232-233
Density
0.90 g/cm3 (20 C)
Solubility in water
Soluble
Partition coefficient, pKow
3.23

Hazards and Protection.
Storage
Store in a tightly closed container. Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.
Handling
Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation. Use only in a chemical fume hood. Wash clothing before reuse.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Provide ventilation.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Moisture, strong oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Autoignition, °C
398
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Flashback vapor along vapor trail may occur.
Combustion products
Irritating fumes of hydrogen chloride may form in fires.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Effects may be delayed.
   Ingestion
May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May be harmful if swallowed.
   Inhalation
Causes respiratory tract irritation. May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. May cause burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
   Skin
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be absorbed through the skin. May cause severe irritation and possible burns.
   Eyes
Causes severe eye irritation. May result in corneal injury. May cause chemical conjunctivitis.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1759
Response guide
Hazard class
8
Packing Group
I; II; III
 
USCG CHRIS Code
HAC