Hexafluoroacetone

  • 1,1,1,3,3,3-Hexafluoroacetone
  • Hexafluoro-2-propanone
  • Perfluoroacetone
  • 2-Propanone, 1,1,1,3,3,3-hexafluoro
Formula
C3F6O
Structure
Description
Colorless gas. Musty odor becomes acrid in presence of acidic impurities.
Uses
chemical intermediate for hexafluoroisopropanol, polyacrylates for textile coating & polyester coating for textiles, solvent for acetal resins & polyamides, polymer adhesive.

Registry Numbers and Inventories.
CAS
684-16-2
EC (EINECS/ELINCS)
211-676-3
R 14 23/25 37/38 41 44
S 23 26 36/37/39 45
RTECS
UC2450000
RTECS class
Reproductive Effector
UN (DOT)
2420
Beilstein/Gmelin
607236
Beilstein Reference
4-01-00-03215
Swiss Giftliste 1
G-4046
Canada DSL/NDSL
NDSL
US TSCA
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C3F6O
Formula mass
166.03
Melting point, °C
-129
Boiling point, °C
-26
Vapor pressure, mmHg
5010 (25 C)
Vapor density (air=1)
1.65
Density
1.65 g/cm3 (25 C)
Solubility in water
Insoluble
Partition coefficient, pKow
1.89
Heat of vaporization
22.5 kJ/mol

Hazards and Protection.
Storage
Store in tightly closed container in a cool location.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors.
Stability
No data.
Incompatibilities
Reacts with many acids and bases liberating heat and flammable gases (e.g., H2) Reacts with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat Incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides Reacts violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Decomposition
Toxic fumes are formed when this material is heated. Reacts with water or acids, producing heat and highly toxic fumes.

Fire.
Flash Point,°C
-24
Fire fighting
Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use alcohol foam, dry chemical or carbon dioxide. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Keep run-off water out of sewers and water sources.
Fire potential
May burn but does not ignite readily.
Hazards
Vapors from liquefied gas are initially heavier than air and spread along ground. Some of these materials may react violently with water. Containers may explode when heated. Ruptured cylinders may rocket.
Combustion products
Emits toxic and/or explosive gases under fire conditions.

Health.
Exposure limit(s)
TLV: 0.1 ppm; 0.68 mg/m3 (as TWA) (skin) (ACGIH 1992-1993) NIOSH REL: TWA 0.1 ppm (0.7 mg/m3) skin
Poison_Class
3
Exposure effects
   Ingestion
Epigastric pain, nausea, dysphagia, salivation, hematemesis, and diarrhea may be noted. These effects may be delayed for several hours following exposure. Gi symptoms are noted when 3 to 5 mg/kg of fluoride are ingested.
   Inhalation
Respirations are first stimulated then depressed. Death is usually from respiratory paralysis. Following inhalation, coughing and choking may be noted.
   Skin
Urticaria and pruritus have been reported following exposure to fluoride.
   Eyes
See Skin.

First aid
 
   Ingestion
Administer milk, calcium gluconate, or calcium lactate to bind fluoride ion in the gastrointestinal tract. Antacids (aluminum and/or magnesium based) should be administered. Iv calcium (gluconate or chloride) and magnesium may be necessary to correct serum deficits of these divalent metals in serious overdosage. Monitor ekg and vital signs.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
2420
Response guide
Hazard class
2.3
PRTC
T
Std. Transport #
4920528