Hexestrol

  • Dihydrodiethylstilbestrol
  • 4,4'-(1,2-Diethylethylene)diphenol
  • meso-3,4-Bis(4-hydroxyphenyl)hexane
  • meso-3,4-Di(p-hydroxyphenyl)-n-hexane
Formula
C18H22O2
Structure
Uses
Estrogen compound used to treat menstrual irregularities and menopausal symptoms and to prevent pregnancy.

Registry Numbers and Inventories.
CAS
84-16-2
EC (EINECS/ELINCS)
201-518-1
RTECS
SL0560850
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector; Hormone
Merck
13,4720
Beilstein/Gmelin
3209460
Beilstein Reference
4-06-00-06761
Japan ENCS (MITI)
Listed

Properties.
Formula
C18H22O2
Formula mass
270.37
Melting point, °C
184 - 185
Boiling point, °C
400
Vapor pressure, mmHg
6E-7 (25 C)
Density
1.063 g/cm3
Solubility in water
70 mg/L (15 C)
pKa/pKb
9.80 (pKa)
Heat of vaporization
67.6 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
182
Fire fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Health
0
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.
   Ingestion
May be harmful if swallowed.
   Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.