- Histamine dihydrochloride
Registry Numbers and Inventories.
R 36/37/38 42/43
S 22 26 36/37/39 45
Drug; Reproductive Effector
Japan ENCS (MITI)
Melting point, °C
Hazards and Protection.
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stable under normal temperatures and pressures.
Strong oxidizing agents.
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Effects may be delayed.
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause flushing followed by pallor, dizziness, fainting, fall in blood pressure, headache, rapid weak pulse, pain, and itching.
Causes respiratory tract irritation. May cause allergic respiratory reaction. May cause effects similar to those described for ingestion. Can produce delayed pulmonary edema. May cause respiratory sensitization.
Causes skin irritation. May cause an allergic reaction in certain individuals. May cause sensitization by skin contact.
Causes eye irritation. May cause chemical conjunctivitis.
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.