Hydrocinchonine

  • Dihydrocinchonine
  • Pseudocinchonine
  • (9S)-10,11-Dihydrocinchonan-9-ol
Formula
C19H24N2O
Structure
Uses
Catalyst for asymmetric synthesis of chiral chromanes.

Registry Numbers and Inventories.
CAS
485-65-4
EC (EINECS/ELINCS)
207-621-8
20/21/22
Merck
12,4824
Beilstein/Gmelin
4296749
Beilstein Reference
6-23

Properties.
Formula
C19H24N2O
Formula mass
296.41
Boiling point, °C
467
Vapor pressure, mmHg
2E-9 (25 C)
Solubility in water
Slightly soluble
pKa/pKb
4.01 (pKb)
Heat of vaporization
76.8 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Incompatibilities
Strong oxidizing agents.
Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Flash Point,°C
236
Fire fighting
Extinguish using Carbon dioxide. Dry chemical powder. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes. Target organ(s): G.I. System.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Transport.