Hydroxyethyl carbamate

  • 1,2-Ethanediol, monocarbamate
  • Ethylene glycol, monocarbamate
  • 2-Hydroxyethylcarbamate
  • beta-Hydroxyethylcarbamate
Formula
C3H7NO3
Structure
Uses
Major uses include formerly a chemical intermediate for textile permanent press finishes.

Registry Numbers and Inventories.
CAS
5395-01-7
EC (EINECS/ELINCS)
226-405-4
RTECS
FB1925000
RTECS class
Mutagen; Reproductive Effector
Beilstein/Gmelin
1746943
Beilstein Reference
4-03-00-00069
Swiss Giftliste 1
G-5864
Japan ENCS (MITI)
Listed

Properties.
Formula
C3H7NO3
Formula mass
105.11
Boiling point, °C
322
Vapor pressure, mmHg
2E-5 (25 C)
Solubility in water
Very soluble
pKa/pKb
13.18 (pKa)
Heat of vaporization
65.3 kJ/mol

Hazards and Protection.

Fire.
Flash Point,°C
148

Health.
Poison_Class
4
Exposure effects
Exposed individuals should have a careful, thorough medical history and physical examination performed looking for any abnormalities. Exposure to chemicals with a strong odor often results in such nonspecific symptoms as headache, dizziness, weakness, and nausea. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases.

First aid
 
   Ingestion
Consider gastric lavage after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Administer charcoal as a slurry 240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old. Immediate dilution with milk or water may be of benefit in caustic or irritant chemical ingestions.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists.
   Eyes
Irrigate eye for at least 20 minutes with water or saline. If irritation persists, seek medical attention.

Transport.