Idebenone

  • 2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl
  • 6-(10-Hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone
  • 6-(10-Hydroxydecyl)ubiquinone
Formula
C19H30O5
Structure
Description
Yellow to yellow-orange solid.

Registry Numbers and Inventories.
CAS
58186-27-9
RTECS
GU5290000
Merck
12,4932
Beilstein/Gmelin
2001459

Properties.
Formula
C19H30O5
Formula mass
338.44
Melting point, °C
52
Boiling point, °C
497
Vapor pressure, mmHg
5.7E-12 (25 C)
Density
1.08 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
15.19 (pKa)
Partition coefficient, pKow
3.49
Heat of vaporization
88.1 kJ/mol

Hazards and Protection.
Storage
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Protection
Safety glasses, lab coat, dust respirator, chemically resistant gloves.
Small spills/leaks
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Oxidizing agents.

Fire.
Flash Point,°C
170
Fire fighting
Extinguish using dry chemical powder, water spray, fog or foam. Do not use water jet.
Fire potential
Slightly flammable to flammable in presence of heat.
Hazards
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
   Ingestion
May cause irritation of the gastrointestinal/digestive tract causing gastritis, anorexia, abdominal pain, vomiting, nausea, hypermotility, diarrhea. May affect respiration (respiratory depression), behavior (lethargy, drowsiness, somnolence).
   Inhalation
Causes irritation.
   Skin
Causes irritation.
   Eyes
Causes irritation.

First aid
 
   Ingestion
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
   Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
   Skin
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
   Eyes
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.

Transport.