Imperatorin

  • Ammidin
  • 6-Hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylic acid omega-lactone
  • 8-Isoamylenoxypsoralen
  • 8-Isopentenyloxypsoralene
  • Marmelosin
  • 9-(3-Methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one
Formula
C16H14O4
Structure
Description
Prisms from ether; long fine needles from hot water.
Uses
Aromatic agent.

Registry Numbers and Inventories.
CAS
482-44-0
EC (EINECS/ELINCS)
207-581-1
RTECS
LV1575000
RTECS class
Mutagen
Merck
12,4960
Beilstein/Gmelin
249728
Beilstein Reference
5-19-06-00016
Swiss Giftliste 1
G-5708

Properties.
Formula
C16H14O4
Formula mass
270.28
Melting point, °C
103
Solubility in water
practically insoluble in cold water

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
3
Exposure effects
dizziness, depression, and headache have been reported with use, as have nervousness and insomnia. Seizures have been reported in animal studies.
   Ingestion
Nausea and abdominal pain have occurred.
   Skin
Erythema and bizarre pigmentation have been seen. Superficial and deep second-degree burns to the skin have been reported following puva therapy. At therapeutic doses, 8-mop will cause more dermal reactions than 5-mop.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
Uv absorbing wrap should be used around sunglasses for 24 hours after methoxsalen ingestions. This decreases the potential for cataract formation.

Transport.