Indeno[1,2,3-cd]pyrene

  • 2,3-Phenylenepyrene
  • o-Phenylenepyrene
Formula
C22H12
Structure
Description
Yellow crystals.
Uses
Research chemical.

Registry Numbers and Inventories.
CAS
193-39-5
EC (EINECS/ELINCS)
205-893-2
RTECS
NK9300000
RTECS class
Tumorigen; Mutagen
UN (DOT)
1325
Beilstein/Gmelin
1879312
Beilstein Reference
4-05-00-02765
RCRA
U137
Canada DSL/NDSL
NDSL
US TSCA
Listed

Properties.
Formula
C22H12
Formula mass
276.34
Melting point, °C
163 - 164
Boiling point, °C
536
Solubility in water
Insoluble

Hazards and Protection.
Storage
Storage should be close to laboratory where material is to be used, so that only small amounts need to be carried. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Small spills/leaks
If you spill this chemical, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Can react exothermically with bases and with diazo compounds.
Decomposition
When heated to decomposition it emits acrid smoke and irritating fumes.

Fire.
Fire fighting
A fire in your laboratory involving this chemical should be extinguished with a dry chemical, carbon dioxide or halon extinguisher.
Fire potential
Flammable/combustible material. May be ignited by friction, heat, sparks or flames.
Combustion products
Fire may produce irritating and/or toxic gases.

Health.
Exposure limit(s)
0.2 mg/m3 PEL
Carcinogin
I-2B, N-2, CP65
Exposure effects
In experimental animal studies, PAHs and metabolites cross the placenta. Female offspring of experimental animals exposed to PAHs during pregnancy have a decrease in the number of functional oocytes, sometimes such that they are infertile. <br>PAHs are lipophilic and are excreted in breast milk, allowing for secondary exposure of nursing infants, although the potential significance of such exposure has not been determined.
   Ingestion
Leukoplakia and cancers of the lip and oral cavity can develop with chronic exposure.
   Inhalation
Irritation, chronic cough, bronchitis, and bronchogenic cancer can occur with chronic exposure.
   Skin
Coal tar warts (precancerous lesions enhanced by uv light exposure), erythema, dermal burns, acneiform lesions, photosensitization and cancer may develop following chronic exposure.
   Eyes
See Skin.

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
1325
Response guide
Hazard class
4.1
Packing Group
II; III
 
USCG CHRIS Code
PPY