Indigo carmine

  • Acid Blue 74
  • 5,5'-Indigodisulfonic acid disodium salt
  • C.I. 73015
  • Food Blue 1
  • Soluble indigo blue
  • 1H-Indole-5-sulfonic acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, disodium salt
Formula
C16H8N2Na2O8S2
Structure
Description
Dark blue powder.
Uses
Used in drugs, cosmetics; baked goods, cereals, snack foods, ice cream, confections, cherries, biscuits, sweets and test kidney function

Registry Numbers and Inventories.
CAS
860-22-0
EC (EINECS/ELINCS)
212-728-8
S 22 36/37
RTECS
DU3000000
RTECS class
Tumorigen; Drug; Mutagen
Merck
13,4969
Beilstein/Gmelin
4103904
Beilstein Reference
2-25-00-00296
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C16H8N2Na2O8S2
Formula mass
466.36
Melting point, °C
>300
Solubility in water
10 g/L (25 C)

Hazards and Protection.
Storage
Keep containers tightly closed. Store protected from light. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents, nitric acid.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Health.
Poison_Class
4 (Substances and products that must be considered harmful)
Exposure effects
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
This product contains a cationic dye. Similar dyes have caused permanant injury to the cornea and conjunctiva in documented exposure cases with human or rabbit eyes.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. SPEEDY ACTION IS CRITICAL!

Transport.
HS Code
3204 12 00