Iodoacetic acid

  • IA
  • MIA
  • Monoiodoacetate
  • Monoiodoacetic acid
Formula
C2H3IO2
Structure
Description
Colorless or white crystals.
Uses
As chemical intermediate & in manufacture of pharmaceuticals & herbicides halogenated acetic acids.

Registry Numbers and Inventories.
CAS
64-69-7
EC (EINECS/ELINCS)
200-590-1
EC Index Number
607-068-00-6
EC Class
Toxic; Corrosive
R 25 35
S 22 36/37/39 45
RTECS
AI3500000
RTECS class
Tumorigen; Mutagen; Reproductive Effector
UN (DOT)
1759
Merck
13,5047
Beilstein/Gmelin
1739079
Beilstein Reference
4-02-00-00534
Swiss Giftliste 1
G-1719
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C2H3IO2
Formula mass
185.96
Melting point, °C
80 - 82
Boiling point, °C
262
Vapor pressure, mmHg
0.0033 (25 C)
Density
2.2694 g/cm3 (85 C)
Solubility in water
Very soluble
Surface tension
38.63 g/s2 (85 C)
pKa/pKb
3.12 (pKa)
Partition coefficient, pKow
0.76
Heat of fusion
15.5 kJ/mol
Heat of vaporization
55.0 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C).
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong bases.
Decomposition
Carbon monoxide, carbon dioxide, iodide.

Fire.
Flash Point,°C
112
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Flash point data for this chemical are not available, but it is probably non-flammable.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
2
Exposure effects
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
May cause respiratory tract irritation.
   Skin
Causes skin burns.
   Eyes
Causes eye burns.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
1759
Response guide
Hazard class
8
Packing Group
I; II; III
 
HS Code
2915 90 80