Ioversol

  • Optiray
  • N,N'-Bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl)-glycola mido]-2,4,6-triiodoisophthalamide
Formula
C18H24I3N3O9
Structure
Description
Odorless white powder.

Registry Numbers and Inventories.
CAS
87771-40-2
RTECS
CZ2229000
Merck
12,5083
Beilstein/Gmelin
7155654

Properties.
Formula
C18H24I3N3O9
Formula mass
807.12
Density
2.265 g/cm3 (20 C)
Solubility in water
Very soluble
pKa/pKb
11.34 (pKa)
Partition coefficient, pKow
-4.01

Hazards and Protection.
Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage.
Protection
Protective gloves, clean body-covering clothing, safety glasses.
Respirators
If the exposure limit is exceeded, a half-face dust/mist respirator may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece dust/mist respirator may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency, or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Small spills/leaks
Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal.
Stability
Stable under ordinary conditions of use and storage. Light sensitive. Hygroscopic.
Decomposition
May emit toxic fumes of nitrogen oxides and iodine when heated to decomposition.

Fire.
Fire fighting
Use any means suitable for extinguishing surrounding fire. Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Fire potential
Not considered to be a fire hazard.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA PEL: 15 mg/m3
Exposure effects
May provoke an allergic reaction in people allergic to iodine or iodinated substances.
   Ingestion
Extremely large oral dosages may produce gastrointestinal disturbances.
   Inhalation
Not expected to be a health hazard.
   Skin
No adverse effects expected.
   Eyes
No adverse effects expected but splashes may cause mechanical irritation.

First aid
 
   Ingestion
If large amounts were swallowed, give water to drink and get medical advice.
   Inhalation
Not expected to require first aid measures.
   Skin
Wash exposed area with soap and water. Get medical advice if irritation develops.
   Eyes
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Call a physician if irritation persists.

Transport.