Ipratropium bromide

  • Atropine isopropyl bromide
  • N-Isopropylatropinium bromide
  • 8-Isopropylatropinium bromide
  • N-Isopropylnoratropinium bromomethylate
  • 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, (endo,syn)-, bromide
Formula
C20H30BrNO3
Structure
Description
White powder.
Uses
Nonselective muscarinic acetylcholine receptor antagonist and bronchodilator.

Registry Numbers and Inventories.
CAS
22254-24-6
EC (EINECS/ELINCS)
244-873-8
20/22 36
RTECS
YM3700000
RTECS class
Drug; Reproductive Effector; Human Data; Primary Irritant
Merck
12,5089
Beilstein/Gmelin
6035562
Beilstein Reference
6-21
Canada DSL/NDSL
DSL

Properties.
Formula
C20H30BrNO3
Formula mass
412.37
Melting point, °C
229 - 231
Solubility in water
10 g/L

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen bromide gas.

Fire.
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful by inhalation and if swallowed. Irritating to eyes. Target organ(s): Nerves.
   Ingestion
Harmful if swallowed.
   Inhalation
Harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.
   Skin
Causes skin irritation. Harmful if absorbed through skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.