Iron dextran

  • Chinofer
  • Dextran iron complex
  • Dextrofer 75
  • Fenate
  • Ferdex 100
  • Ferric dextran
Formula
Unspecified
Description
Dark reddish-brown liquid.
Uses
Medication.

Registry Numbers and Inventories.
CAS
9004-66-4
RTECS
NI2200000
RTECS class
Tumorigen; Drug; Reproductive Effector; Human Data
Beilstein/Gmelin
NA
RCRA
U139
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Solubility in water
extremely soluble

Hazards and Protection.
Storage
Storage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Dispensers of liquid detergent should be available. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, and disposable plastic aprons might provide additional protection. Protective clothing should be of distinctive color, as a reminder not to be worn outside the laboratory.
Respirators
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Small spills/leaks
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
Complex is unstable @ pH 5; it does not undergo autoxidation @ ambient temperature, but this does occur @ 65-70 C. Expiration date of 5 yr following date of mfr.
Incompatibilities
Sensitive to prolonged exposure to air.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This chemical is combustible.

Health.
Carcinogin
I-2B, N-2, CP65
Exposure effects
dizziness and headache have been reported, along with a cluster of other symptoms, 1 to 2 days after administration.
   Ingestion
Gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea) have been reported .
   Inhalation
Dyspnea and bronchospasm have been reported with iron dextran and appear related to an anaphylactic response.
   Skin
Urticaria, pruritus, purpura and skin discoloration have been reported following the use of iron dextran.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.