Iron sorbitex

  • Iron sorbitol citrate
  • Yectofer
  • Jectofer
Brown colloidal solution.

Registry Numbers and Inventories.
RTECS class

1.17-1.19 g/cm3 (20 C)

Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stable in serum.
Strong oxidizing agents.

Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Exposure effects
Blood pressure may be decreased following an iron overdose. Lethargy, restlessness or confusion may be seen early in the poisoning. Convulsions and coma may occur in later phases. Case reports of pregnant women who have received early aggressive treatment (decontamination and/or deferoxamine) have described good fetal outcomes.
Nausea, vomiting, diarrhea and gastrointestinal hemorrhage may develop.
Noncardiogenic pulmonary edema may develop with severe intoxication.
Severe thermal burn with ferrous sulfate slurry has caused classical symptoms of ingested iron poisoning.

First aid
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
Diagnosis of iron intraocular foreign body can be done by x-ray, by computerized tomography, by establishing that the foreign body can be moved with a magnet, and by electroretinogram. Magnetic resonance imaging is not recommended as movement of the foreign body may result.