Isazofos

  • O-5-Chloro-1-isopropyl-1 h-1,2,4-triazol-3-yl O,O-diethyl phosphorothioate
  • O-(5-Chloro-1-isopropyl-1,2,4-triazol-3-yl) O,O-diethyl phosphorothioate
Formula
C9H17ClN3O3PS
Structure
Description
Amber liquid.
Uses
Isazofos is a soil-applied nematicide with contact and systemic properties.

Registry Numbers and Inventories.
CAS
42509-80-8
EC (EINECS/ELINCS)
255-863-8
EC Index Number
015-153-00-9
EC Class
Very toxic; Toxic; Harmful; Sensitising; Dangerous for the Environment
RTECS
TE7760000
RTECS class
Agricultural Chemical and Pesticide; Mutagen
Merck
12,5119
Beilstein/Gmelin
8145294
EPA OPP
126901
Swiss Giftliste 1
G-1975
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C9H17ClN3O3PS
Formula mass
313.74
Boiling point, °C
100
Vapor pressure, mmHg
9E-5
Density
1.22 g/cm3 (20 C)
Solubility in water
69 mg/L at 20 C
Refractive index
1.4867 (20 C)
pKa/pKb
4.0 (pKa)
Partition coefficient, pKow
3.1

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
2
Exposure effects
Reduced body temperature or elevated body temperature may occur. Low heart rate and abnormally low blood pressure may develop after moderate to severe poisoning. Rapid heart rate, elevated blood pressure, and changes in respiratory rate may also occur. Early giddiness, anxiety headache, and restlessness followed by ataxia, drowsiness, and confusion are common with moderate to severe exposures. Sporadic reports of human birth defects related to organophosphates have not been fully verified.
   Ingestion
Nausea, vomiting, abdominal cramps, and diarrhea are common muscarinic effects. Both painless and frank clinical pancreatitis have been reported.
   Skin
Profuse sweating is common. Pallor may be noted. Dermal sensitization has been reported.
   Eyes
Constriction of the pupil, tearing, and blurred vision are common. Prolonged dialation of the pupils may occur. Salivation commonly occurs.

First aid
 
   Ingestion
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.