Isoamyl alcohol

  • 3-Methyl-1-butanol
  • Isobutylcarbinol
  • Isopentyl alcohol
  • 3-Methylbutan-1-ol
Formula
(CH3)2CHCH2CH2OH
Structure
Description
Colorless liquid, with a disagreeable sweet odor.
Uses
Synthetic flavor, intermediate in prepn of pharmaceuticals, for isoamyl acetate and other esters, for dithiophosphate esters (lubricating oil additive and hydraulic fluid additive).

Registry Numbers and Inventories.
CAS
123-51-3
EC (EINECS/ELINCS)
204-633-5
EC Index Number
603-006-00-7
EC Class
flammable, harmful
R 10 20
RTECS
EL5425000
RTECS class
Tumorigen; Human Data; Primary Irritant
UN (DOT)
1105
Merck
13,5214
Beilstein/Gmelin
1718835
Beilstein Reference
4-01-00-01677
Swiss Giftliste 1
G-2436
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C5H12O
Formula mass
88.15
Melting point, °C
-117
Boiling point, °C
130
Vapor pressure, mmHg
5 (32 C)
Vapor density (air=1)
3
Saturation Concentration
Approximately 2000-3000 ppm (0.2-0.3%) at 20 C; approximately 4000 ppm (0.4%) at 25 C (calculated)
Evaporization number
0.19 (n-butyl acetate = 1)
Odor Threshold Odor threshold 25 mg/m3
Critical temperature
304
Critical pressure
38.8
Density
0.812 g/cm3 (20 C)
Solubility in water
20 g/L
Viscosity
4.37 cp (20 C)
Surface tension
23.73 g/s2 (20 C)
Refractive index
1.4075 (20 C)
Dipole moment
1.7 D (20 C)
Dielectric constant
14.7 (20 C)
Partition coefficient, pKow
1.16
Heat of vaporization
44.23 kJ/mol
Heat of combustion
-3415 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B3 D2B
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not get on skin or in eyes. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Prevent spreading of vapors through sewers, ventilation systems and confined areas.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents. Substance reacts explosively with hydrogen trisulfide and strongly with reducing materials.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
45
Autoignition, °C
335
Upper exp. limit, %
8
Lower exp. limit, %
1.2
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. May polymerize explosively when involved in a fire. Containers may explode if exposed to fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
Moderate - combustion with moderate heating.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Toxic gases and vapors (such as carbon monoxide) may be released in a fire involving isoamyl alcohol.
Health
1
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA PEL: TWA 100 ppm (360 mg/m3) NIOSH REL: TWA 100 ppm (360 mg/m3) ST 125 ppm (450 mg/m3) NIOSH IDLH: 500 ppm
Poison_Class
4
Exposure effects
Headache, dizziness, giddiness, ataxia, sedation and coma may occur.
   Ingestion
May cause irritation of the digestive tract. May cause a narcotic effect with possible coma. May be harmful if swallowed.
   Inhalation
Causes respiratory tract irritation. Causes narcotic effects including headache, dizziness, weakness, unconsciousness, and possible death. May cause visual abnormalities.
   Skin
Causes skin irritation. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1105
Response guide
Hazard class
3
Packing Group
II; III
 
USCG CHRIS Code
IAA
 
20 Alcohols, Glycols
HS Code
3824 90 99
 
IMO Chemical Code
18
IMO Pollution Category
D