Isobutyl alcohol

  • 2-Methyl-1-propanol
  • Isobutanol
  • IBA
  • Isopropylcarbinol
  • 2-Methylpropan-1-ol
Formula
(CH3)2CHCH2OH
Structure
Description
Clear, colorless liquid with a sweet, musty odor.
Uses
Production of esters for fruit flavoring essences.

Registry Numbers and Inventories.
CAS
78-83-1
EC (EINECS/ELINCS)
201-148-0
EC Index Number
603-108-00-1
EC Class
Flammable; Irritant; Vapours may cause drowsiness and dizziness
R 10 37/38 41 67
S 7/9 13 26 37/39 46
RTECS
NP9625000
RTECS class
Tumorigen; Mutagen
UN (DOT)
1212
Merck
13,5148
Beilstein/Gmelin
1730878
Beilstein Reference
4-01-00-01588
RCRA
U140
EPA OPP
1507
Swiss Giftliste 1
G-2523
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H10O
Formula mass
74.12
Melting point, °C
-108
Boiling point, °C
107.9
Vapor pressure, mmHg
10 (25 C)
Vapor density (air=1)
2.55
Saturation Concentration
11580 ppm at 20 C
Evaporization number
0.8 (buyl acetate = 1)
Odor Threshold Odor threshold 40 ppm
Critical temperature
274.63
Critical pressure
0.041
Density
0.802 g/cm3 (20 C)
Solubility in water
95 g/L
Viscosity
2.85 cp (30 C)
Surface tension
23.0 g/s2 in contact with vapor at 20 C
Refractive index
1.3976 (20 C)
Dipole moment
1.79 D (20 C)
Dielectric constant
17.7 (20 C)
Partition coefficient, pKow
0.76
Heat of vaporization
50.76 kJ/mol
Heat of combustion
-2670 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
B2 D2B
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents, inorganic acids, aldehydes, isocyanates.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
28
Autoignition, °C
415
Upper exp. limit, %
1-.6
Lower exp. limit, %
1.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Fire potential
Highly flammable. Can release vapors that form explosive mixtures at temperatures above the flashpoint.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Toxic gases and vapors (such as carbon monoxide) may be released in a fire involving isobutyl alcohol.
Health
1
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV: 50 ppm; 152 mg/m3 (as TWA) (ACGIH 1994-1995). MAK: 100 ppm; 300 mg/m3 (1994). OSHA PEL: TWA 100 ppm (300 mg/m3) NIOSH REL: TWA 50 ppm (150 mg/m3) NIOSH IDLH: 1600 ppm
Poison_Class
4
Exposure effects
Effects may be delayed. Prolonged or repeated skin exposure may cause dermatitis.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause corneal abnormalities and loss of appetite and weight. May cause burning sensation in the chest.
   Skin
Skin contact causes irritation, redness, and pain. May be absorbed through the skin; symptoms of absorption may be similar to those from ingestion exposure.
   Eyes
May cause severe eye irritation. May cause chemical conjunctivitis and corneal damage. Vapors cause irritation, redness, and blurred vision.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration.
   Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1212
Response guide
Hazard class
3
Packing Group
III
 
USCG CHRIS Code
IAL
 
20 Alcohols, Glycols
HS Code
2905 14 90
 
Std. Transport #
4909124 4909191 4912264 4912870
 
IMO Chemical Code
18
IMO Pollution Category
III