Isoferulic acid

  • Hesperetic acid
  • 3-Hydroxy-4-methoxycinnamic acid
  • 2-Propenoic acid, 3-(3-hydroxy-4-methoxyphenyl)
Formula
C10H10O4
Structure
Description
Off-white solid.

Registry Numbers and Inventories.
CAS
537-73-5
EC (EINECS/ELINCS)
208-676-0
R 36/37/38
RTECS
UD3365400
RTECS class
Drug
Beilstein/Gmelin
2212760
Beilstein Reference
4-10-00-01777
New Zealand
Listed

Properties.
Formula
C10H10O4
Formula mass
194.19
Melting point, °C
180 - 182
Boiling point, °C
410
Vapor pressure, mmHg
2E-7 (25 C)
Solubility in water
Very soluble
pKa/pKb
3.98 (pKa)
Partition coefficient, pKow
1.56
Heat of vaporization
69.9 kJ/mol
Heat of combustion
-4701 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. No special precautions indicated.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
168
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
4 (Substances and products that must be considered harmful)
Exposure effects
   Ingestion
May cause irritation of the digestive tract. Low hazard for usual industrial handling.
   Inhalation
May cause respiratory tract irritation. Low hazard for usual industrial handling.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water. Get medical aid if irritation or symptoms occur.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Transport.
HS Code
2918 90 90