Isophorone diisocyanate

  • 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate
  • 1,1,5,5-Tetramethylcyclohexane-a-1,3-diisocyanate
  • 5-Isocyanato-1-isocyanatomethyl-1,3,3-trimethylcoclohexane
Formula
C12H18N2O2
Structure
Description
Colorless to slightly yellow liquid with a pungent odor.
Uses
Yields polyurethanes with high stability, resistance to light discoloration, and chemical resistance.

Registry Numbers and Inventories.
CAS
4098-71-9
EC (EINECS/ELINCS)
223-861-6
EC Index Number
615-008-00-5
EC Class
Toxic; Irritant; Sensitising; Dangerous for the Environment
R 23 36/37/38 42/43 51/53
S 26 28 38 45 61
RTECS
NQ9370000
RTECS class
Reproductive Effector
UN (DOT)
2290
Beilstein/Gmelin
2726467
Beilstein Reference
6-13
Swiss Giftliste 1
G-6847
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C12H18N2O2
Formula mass
222.29
Melting point, °C
-60
Boiling point, °C
158
Vapor pressure, mmHg
0.0003
Saturation Concentration
0.40-0.53 ppm at 20 C (calculated)
Evaporization number
Probably very low
Density
1.049 g/cm3 (20 C)
Solubility in water
Reacts
Refractive index
1.482 (25 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
D1A D2A D2B
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Do not use water.
Disposal code
9
Stability
No data.
Incompatibilities
Reacts with all substances containing active hydrogen atoms such as water, alcohols, phenols, amines, mercaptans, amides, urethanes and ureas.

Fire.
Flash Point,°C
155
Autoignition, °C
430
Upper exp. limit, %
4.5
Lower exp. limit, %
0.7
Fire fighting
Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site.Small fires: dry chemical, carbon dioxide, water spray or foam. Large fires: water spray, fog or foam. Move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.
Fire potential
Combustible material: may burn but does not ignite readily.
Hazards
When heated to decomposition, it emits toxic fumes of nitrogen oxides.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
1
 
 
Reactivity
1
 
 
Special
W

Health.
Exposure limit(s)
TLV: 0.005 ppm; 0.045 mg/m3 (skin) (ACGIH 1991-1992). NIOSH REL: TWA 0.005 ppm (0.045 mg/m3) ST 0.02 ppm (0.180 mg/m3) skin
Poison_Class
2
Exposure effects
No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation.
   Ingestion
Gastrointestinal tract irritation could potentially occur.
   Inhalation
Respiratory tract irritation may occur. Pulmonary sensitization with bronchospasm on re-exposure is possible. Released oxides of nitrogen could produce severe irritation or pulmonary edema.
   Skin
Direct contact produces skin irritation. Dermal hypersensitivity reactions may be seen on re-exposure.
   Eyes
Irritation may result from direct eye contact. Exposure to vapors may produce irritation to the mucosa of the nose and throat.

First aid
 
   Ingestion
Do not induce vomiting - consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Observe patients with ingestion carefully for the possible development of esophageal or gastrointestinal tract irritation or burns. If signs or symptoms of esophageal irritation or burns are present, consider endoscopy to determine the extent of injury.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Systemic antihistamine or corticosteroid therapy may be required for hypersensitivity reactions.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. As severe ocular injury may occur with direct eye contact, consider early ophthalmologic consultation.

Transport.
UN number
2290
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
IPD
 
HS Code
2929 10 90
 
Std. Transport #
4925107
 
IMO Chemical Code
17
IMO Pollution Category
B
IMO Hazard code
S/P