Isopregnanolone

  • Allopregnanolone
  • 5a-Pregnan-3b-ol-20-one
  • 5a-Dihydropregnenolone
  • 3b-Hydroxy-5a-pregnan-20-one
  • 3b-Hydroxy-5a-tetrahydroprogesterone
  • 3b-Allopregnanolone
Formula
C21H34O2
Structure
Uses
Neuroactive progesterone metabolite.

Registry Numbers and Inventories.
CAS
516-55-2
EC (EINECS/ELINCS)
208-224-2
RTECS
TU4383200
RTECS class
Drug
Merck
12,284
Beilstein/Gmelin
1915181
Beilstein Reference
5-08

Properties.
Formula
C21H34O2
Formula mass
318.5
Melting point, °C
188 - 189
Boiling point, °C
431
Vapor pressure, mmHg
3E-9 (25 C)
Solubility in water
Insoluble
Heat of vaporization
79.3 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store in a cool dry place.
Protection
Compatible chemical-resistant gloves.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
184
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
The chemical, physical, and toxicological properties of this product have not been thoroughly investigated. Exercise due care.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Transport.