Isopropanol

  • 2-Propanol
  • Isopropyl alcohol
  • Propan-2-ol
Formula
CH3CH(OH)CH3
Structure
Description
Colorless liquid with a sharp, musty odor of rubbing alcohol.
Uses
Microbiocide, Solvent.

Registry Numbers and Inventories.
CAS
67-63-0
EC (EINECS/ELINCS)
200-661-7
EC Index Number
603-117-00-0
EC Class
Highly flammable; Irritant; Vapours may cause drowsiness and dizziness
R 11 36 67
S 7 16 24/25 26
RTECS
NT8050000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
1219
Merck
13,5228
Beilstein/Gmelin
635639
Beilstein Reference
4-01-00-01461
EPA OPP
47501
Swiss Giftliste 1
G-1712
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H8O
Formula mass
60.10
Melting point, °C
-89
Boiling point, °C
82
Vapor pressure, mmHg
44 (25 C)
Vapor density (air=1)
2.1
Saturation Concentration
43600 ppm (4.36%) at 20 C; 59700 ppm (5.97%) at 25 C (calculated)
Evaporization number
2.83 (butyl acetate=1)
Odor Threshold Odor threshold 90 mg/m3
Critical temperature
235
Critical pressure
47.00
Density
0.786 g/cm3
Solubility in water
Miscible
Viscosity
2.08 cp (25 C)
Surface tension
21.19 g/s2 (25 C)
Refractive index
0.3852 (20 C)
Dipole moment
1.66 D (20 C)
Dielectric constant
18.3 (25 C)
Partition coefficient, pKow
0.05
Heat of fusion
5.4 kJ/mol
Heat of vaporization
28.3 kJ/mol
Heat of combustion
-1995 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.
B2 D2A D2B
Handling
Wash thoroughly after handling. Wash hands before eating. Use only in a well ventilated area. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not get on skin or in eyes. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Neoprene and nitrile rubber are recommended materials. Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Respirators
A full facepiece respirator with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition.
Disposal code
1
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. This material may be sensitive to peroxide formation. Heat and sunlight can contribute to instability.
Incompatibilities
Oxidizing agents, aldehydes, acetaldeyde, chlorine, ethylene oxide, acids and isocyanates, hydrogen + palladium, nitroform, oleum, phosgene, potassium t-butoxide, oxygen, trinitromethane, barium perchlorate, tetrafluoroborate, nitric acid, halogen and halogen compounds, chromium trioxide, sodium dichromate + sulfuric acid, aluminum, and aluminum triisopropoxide. It has also been reported to be susceptible to autoxidation and should therRefer to therefore be considered peroxidizable. NFPA manual for more specific information.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
12
Autoignition, °C
399
Upper exp. limit, %
12.7
Lower exp. limit, %
2.0
Fire fighting
Use water in flooding quantities as fog. Use foam, dry chemical, or carbon dioxide. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use water spray to knock-down vapors. Keep run-off water out of sewers and water sources.
Fire potential
HIGHLY FLAMMABLE.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
1
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA PEL: TWA 400 ppm (980 mg/m3) NIOSH REL: TWA 400 ppm (980 mg/m3) ST 500 ppm (1225 mg/m3) NIOSH IDLH: 2000 ppm LEL
Poison_Class
-
Exposure effects
Prolonged or repeated skin contact may cause defatting and dermatitis. May cause allergic skin reaction in some individuals.
   Ingestion
Can cause drowsiness, unconsciousness, and death. Gastrointestinal pain, cramps, nausea, vomiting, and diarrhea may also result. The single lethal dose for a human adult = about 250 mls (8 ounces).
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Inhalation of vapor may cause respiratory tract irritation. May cause narcotic effects.
   Skin
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause irritation with pain and stinging, especially if the skin is abraded.
   Eyes
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
1219
Response guide
Hazard class
3
Packing Group
II
 
USCG CHRIS Code
IPA
 
20 Alcohols, Glycols
HS Code
2905 12 00
 
Std. Transport #
4907810
 
IMO Chemical Code
18
IMO Pollution Category
III