Isopropanolamine

  • 1-Amino-2-propanol
  • Threamine
  • 1-Aminopropan-2-ol
  • DL-1-Amino-2-propanol
Formula
H2NCH2CH(OH)CH3
Structure
Description
Colorless, crystalline mass or viscous liquid, if over the melting point.
Uses
Emulsifying agent, dry cleaning, soaps, soluble textile oils, wax removers, metal cutting oils, cosmetics, emulsion paints, plasticizers, insecticides.

Registry Numbers and Inventories.
CAS
78-96-6
EC (EINECS/ELINCS)
201-162-7
EC Index Number
603-082-00-1
EC Class
Corrosive
S 23 26 36 45
RTECS
UA5775000
RTECS class
Reproductive Effector; Primary Irritant
UN (DOT)
2735
Beilstein/Gmelin
605275
Beilstein Reference
4-04-00-01665
Swiss Giftliste 1
G-6278
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H9NO
Formula mass
75.11
Melting point, °C
1
Boiling point, °C
158 - 160
Vapor pressure, mmHg
0.86 (25 C)
Vapor density (air=1)
3.0
Saturation Concentration
1840 ppm (0.2%) at 20 C (calculated)
Critical temperature
328
Critical pressure
58
Density
0.9769 g/cm3 (0 C)
Solubility in water
Very soluble
Refractive index
1.44786 (18 C)
Dipole moment
2.57 (20 C)
pKa/pKb
4.82 (pKb)
Partition coefficient, pKow
-0.96
Heat of vaporization
46.2 kJ/mol
Heat of combustion
-2360 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Store protected from moisture.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Disposal code
1
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Copper, brass, aluminum, and oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
67
Autoignition, °C
335
Upper exp. limit, %
10.4
Lower exp. limit, %
1.9
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool Extinguishing media: Use water spray to cool fire-exposed containers. Use alcohol foam to extinquish.
Fire potential
Combustible Liquid and Vapor.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Combustion products
Irritating vapors generated when heated.
Health
2
 
Flammability
2
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OEL-RUSSIA:STEL 1 mg/m3;Skin
Poison_Class
4
Exposure effects
May cause reproductive effects.
   Ingestion
May cause severe and permanent damage to the digestive tract. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May be harmful if swallowed.
   Inhalation
Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath.
   Skin
Causes severe irritation with redness, pain, and possibly skin burns.
   Eyes
Causes severe irritation. May cause redness, pain, blurred vision, and eye damage.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Transport.
UN number
2735
Response guide
Hazard class
8
Packing Group
I; II; III
 
USCG CHRIS Code
MPA
 
HS Code
2922 19 80
 
Std. Transport #
4935626
 
IMO Chemical Code
17
IMO Pollution Category
C
IMO Hazard code
S/P