Isopropyl formate

  • Formic acid, 1-methylethyl ester
  • Formic acid, isopropyl ester
Formula
C4H8O2
Structure
Description
Colorless liquid. Pleasant odor.
Uses
A toxic fumigant.

Registry Numbers and Inventories.
CAS
625-55-8
EC (EINECS/ELINCS)
210-901-2
EC Index Number
607-016-00-2
EC Class
Highly flammable; Irritant; Vapours may cause drowsiness and dizziness
R 11 36/37 67
S 9 16 24 33
RTECS
LQ8750000
RTECS class
Agricultural Chemical and Pesticide
UN (DOT)
1281
Beilstein/Gmelin
1735844
Beilstein Reference
4-02-00-00027
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C4H8O2
Formula mass
88.12
Melting point, °C
-89
Boiling point, °C
67 - 68
Vapor pressure, mmHg
138
Vapor density (air=1)
3.03
Critical temperature
277
Critical pressure
41.8
Density
0.8826 g/cm3 (0 C)
Solubility in water
Slightly soluble
Surface tension
22.44 g/s2 (19 C)
Refractive index
1.3659 (20 C)
Partition coefficient, pKow
0.5

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear full protective clothing and positive pressure self contained breathing apparatus.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Make no contact with the spilled material. ELIMINATE all ignition sources and ground all equipment. Stop leak if you can do it without risk. A vapor suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean non-sparking tools to collect absorbed material.
Stability
No data.
Incompatibilities
Can react vigorously with oxidizing materials. Hydrolyzes with water to isopropyl alcohol and formic acid which is toxic.

Fire.
Flash Point,°C
12.2 (closed cup)
Fire fighting
Use water spray, alcohol foam, dry chemical or carbon dioxide. Water may be ineffective.
Fire potential
Dangerous, when exposed to heat or flame. Flammable
Hazards
Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure effects
Dizziness and loss of consciousness may occur after exposure to high airborne concentrations. No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation.
   Ingestion
Mild to moderate oral and esophageal irritation may occur.
   Inhalation
Irritation of the lungs and bronchial tree may be seen.
   Skin
Irritation or possibly burns of the skin may be seen after direct exposure to the liquid.
   Eyes
See Skin.

First aid
 
   Ingestion
Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
1281
Response guide
Hazard class
3
Packing Group
II