Colorless crystalline solid.
Herbicide, plant growth regulator.
Registry Numbers and Inventories.
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
87-89 (0.005 torr)
1.09 g/cm3 (20 C)
Solubility in water
Partition coefficient, pKow
Hazards and Protection.
Keep in well ventilated area.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Self-contained breathing apparatus must be worn. Rubber gloves, hats, suits and boots must be worn.
Wear positive pressure self-contained breathing apparatus (SCBA).
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Incompatible with strong acids and bases, and especially
Use method most appropriate to fight surrounding fire.
Fire may produce irritating, corrosive and/or toxic gases.
Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.
Nausea, vomiting and diarrhea may occur.
Respiratory failure, requiring ventilatory support, has been reported following ingestions.
Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.
Ipecac-induced vomiting is not recommended because of the potential for cns depression and seizures. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Intravenous fluids may be useful in restoring extracellular fluid volume following severe vomiting and diarrhea.
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
Immediately flush with running water for at least 20 minutes.
I; II; III