Isopropyl-n-phenyl carbamate

  • isopropil-n-fenil-carbammato
  • isopropyl-n-fenyl-carbamaat
Formula
C10H13NO2
Structure
Description
Colorless crystalline solid.
Uses
Herbicide, plant growth regulator.

Registry Numbers and Inventories.
CAS
122-42-9
EC (EINECS/ELINCS)
204-542-0
RTECS
FD9100000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data
UN (DOT)
2757
Merck
12,8001
Beilstein/Gmelin
2209666
Beilstein Reference
4-12-00-00620
RCRA
U373
EPA OPP
47601
Swiss Giftliste 1
G-1652
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C10H13NO2
Formula mass
179.22
Melting point, °C
90
Boiling point, °C
87-89 (0.005 torr)
Density
1.09 g/cm3 (20 C)
Solubility in water
practically insoluble
Partition coefficient, pKow
2.60

Hazards and Protection.
Storage
Keep in well ventilated area.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Self-contained breathing apparatus must be worn. Rubber gloves, hats, suits and boots must be worn.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Stable.
Incompatibilities
Incompatible with strong acids and bases, and especially

Fire.
Fire fighting
Use method most appropriate to fight surrounding fire.
Fire potential
Nonflammable.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Poison_Class
4
Exposure effects
Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.
   Ingestion
Nausea, vomiting and diarrhea may occur.
   Inhalation
Respiratory failure, requiring ventilatory support, has been reported following ingestions.
   Skin
Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Ipecac-induced vomiting is not recommended because of the potential for cns depression and seizures. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Intravenous fluids may be useful in restoring extracellular fluid volume following severe vomiting and diarrhea.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Immediately flush with running water for at least 20 minutes.

Transport.
UN number
2757
Response guide
Hazard class
6.1
Packing Group
I; II; III