Kadethrin

  • 5-Benzyl-3-furylmethyl (e)-(1r)-cis-2,2-dimethyl-3-(2-oxothiolan-3-ylidenemethyl)cyclopropanecarboxylate
  • 5-Benzyl-3-furylmethyl(e)-(1r,3s)-2,2-dimethyl-3-(2-oxothiolan-3-ylidenemethyl)cyclopropanecarboxylate
  • 3-oxo-3(2H)-Thienylidene)methyl]-2,2-dimethylcyclopropanecarboxylate
  • Ru 15525
  • Spray-Tox
Formula
C23H24O4S
Structure
Description
Yellow-brown viscous oil.
Uses
Insecticide.

Registry Numbers and Inventories.
CAS
58769-20-3
EC (EINECS/ELINCS)
261-433-0
RTECS
GZ1266550
RTECS class
Agricultural Chemical and Pesticide
Beilstein/Gmelin
1605066
EPA OPP
97803
Korea ECL
Listed

Properties.
Formula
C23H24O4S
Formula mass
396.53
Melting point, °C
31
Vapor pressure, mmHg
< 0.1 mPa @ 20 C
Solubility in water
practically insoluble

Hazards and Protection.
Storage
For storage, aluminum cans or cans lacquered on the inside are recommended (not tinplate). Pyrethrins with piperonyl butoxide topical preparations should be stored in well-closed containers at a temperature less than 40C, preferably between 15-30C.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Employees should be provided with and required to use dust- and splash-proof safety goggles where pyrethroids may contact the eyes. Employees should be provided with and be required to use impervious clothing, gloves, and face shields (eight-inch minimum). Wear appropriate equipment to prevent: repeated or prolonged skin contact. Wear eye protection to prevent: reasonable probability of eye contact.
Respirators
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure mode. Any supplied-air respirator with a full face piece and operated in pressure-demand or other positive pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive pressure mode
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
Hydrolyzed by aqueous alkalis. Rapidly decomposed by light (more slowly in mineral oils). Unstable to heat. Are stable for long periods in water-based aerosols where emulsifiers give neutral water systems.
Incompatibilities
Incompatible with alkaline materials, strong oxidizers. Incompatible with lime and ordinary soaps because acids and alkalies speed up processes of hydrolysis.

Fire.
Fire fighting
Use carbon dioxide, foam, or dry chemical on fires involving pyrethroids.

Health.
Exposure effects
   Ingestion
Nausea, vomiting and abdominal pain commonly occur and develop within 10 to 60 minutes following ingestion.
   Inhalation
Hypersensitivity reactions characterized by pneumonitis, cough, dyspnea, wheezing, chest pain, and bronchospasm may occur. Rare cases of respiratory failure and cardiopulmonary arrest have been reported.
   Skin
Irritant and contact dermatitis may develop. Erythema which mimics sunburn has also been noted after prolonged repeated exposure.

First aid
 
   Ingestion
There is no specific antidote for pyrethrin poisoning. Treatment is symptomatic and supportive and includes monitoring for the development of hypersensitivity reactions with respiratory distress. Provide adequate airway management when needed. Gastric decontamination is usually not required unless the pyrethrin product is combined with a hydrocarbon. Allergic reaction: mild: antihistamines with or without epinephrine. Severe: oxygen, aggressive airway management, antihistamines, epinephrine (adult: 0.3 To 0.5 Ml of a 1:1000 solution subcutaneously; child: 0.01 Ml/kg; may repeat in 20 to 30 min), corticosteroids, ecg monitoring, and iv fluids.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Vitamin e topical application is highly effective in relieving paresthesias.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.