Kainic acid

  • Digenic acid
  • Digenin
  • Helminal
  • L-alpha-Kainic acid
  • 3-Pyrrolidineacetic acid, 2-carboxy-4-isopropenyl
  • (2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic acid
Formula
C10H15NO4
Structure
Description
White to light yellow solid.
Uses
Neurobiological tool.

Registry Numbers and Inventories.
CAS
487-79-6
R 20/21/22
RTECS
UX9665250
Merck
12,5289
Beilstein/Gmelin
86660
Beilstein Reference
4-22-00-01523
Japan ENCS (MITI)
Listed

Properties.
Formula
C10H15NO4
Formula mass
213.23
Melting point, °C
251
Boiling point, °C
440
Vapor pressure, mmHg
5.7E-9 (25 C)
Density
1.22 g/cm3
Solubility in water
Soluble
pKa/pKb
2.03 (pKa)
Partition coefficient, pKow
0.496
Heat of vaporization
76.41 kJ/mol

Hazards and Protection.
Storage
Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 4 C.
Protection
Splash goggles. Full suit. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Respirators
A self-contained breathing apparatus should be used to avoid inhalation of the product.
Small spills/leaks
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Stability
Stable under normal temperatures and pressures.

Fire.
Flash Point,°C
220
Fire fighting
For small fires, use dry chemical powder. For large fires, use water strap, fog or foam. Do not use water jet. Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear.
Fire potential
May be combustible at high temperature.
Combustion products
Oxides of carbon and nitrogen.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
May be harmful if inhaled, absorbed through the skin or swallowed. May cause damage to the brain.

First aid
 
   Ingestion
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
   Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
   Skin
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
   Eyes
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.

Transport.