Kepone

  • Chlordecone
  • Decachlorooctahydro-kepone-2-one
  • Decachlorotetrahydro-4,7-methanoindeneone
  • Decachlorooctahydro-1,3,4-metheno-2H-Cyclobuta(Cd)-Pentalen-2-one
Formula
C10Cl10O
Structure
Description
Odorless colorless crystalline solid.
Uses
Insecticide for bananas, non-bearing citrus trees (former use), tobacco (former use), ornamental shrubs, insects in buildings (former use), lawns, turf, & flowers (former use), indoor & outdoor areas (former use).

Registry Numbers and Inventories.
CAS
143-50-0
EC (EINECS/ELINCS)
205-601-3
EC Index Number
606-019-00-6
EC Class
Carcinogenic Category 3; Toxic; Dangerous for the Environment
RTECS
PC8575000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector
UN (DOT)
2761
Merck
12,2131
Beilstein/Gmelin
1894593
RCRA
U142
EPA OPP
27701
Swiss Giftliste 1
G-2478
Austrailia AICS
Listed

Properties.
Formula
C10Cl10O
Formula mass
490.64
Boiling point, °C
434
Decomposition point, °C
350
Vapor pressure, mmHg
1E-7 (25 C)
Vapor density (air=1)
16.94
Odor Threshold Odor threshold Odorless
Solubility in water
0.05 g/100 ml (hot water)
Partition coefficient, pKow
6.08
Heat of vaporization
69.0 kJ/mol

Hazards and Protection.
Storage
Tightly closed containers. Keep away from heat and water.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
Stable to about 350 C; readily hydrates on exposure to room temperature and humidity.
Incompatibilities
Reacts with many acids and bases liberating heat and flammable gases (e.g., H2) Reacts with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat Incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides Reacts violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Decomposition
See chlorides. Dangerous when heated to decomp. Evolve highly toxic chloride fumes.

Fire.
Flash Point,°C
183
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is probably combustible.

Health.
Exposure limit(s)
NIOSH REL: Ca TWA 0.001 mg/m3 See Appendix A
Carcinogin
I-2B, N-2, CP65
Poison_Class
1
Exposure effects
CNS excitation, seizures, tremor, ataxia, agitation, nervousness, and amnesia may occur. Kelthane, perthane, methoxychlor, and hexachlorobenzene have little CNS toxicity; in extreme overdose CNS depression may occur. Organochlorine pesticides such as DDT pass through the placenta, with an average level in the newborn blood reaching around a third of that in maternal blood. They can also be found in breast milk. Excessive absorption of kepone (chlordecone) has depressed sperm counts and sperm motility in exposed workers.
   Ingestion
Nausea, vomiting, and diarrhea may follow ingestion.
   Inhalation
Aspiration of insecticide containing petroleum distillate may result in pneumonitis.
   Skin
Extensive contact results in dermal irritation.

First aid
 
   Ingestion
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
2761
Response guide
USCG CHRIS Code
KPE