Ketoprofen

  • 2-(3-Benzoylphenyl)propionic acid
  • 3-Benzoylhydratropic acid
  • 3-Benzoyl-a-methylbenzeneacetic acid
Formula
C16H14O3
Structure
Uses
Non-steroidal anti-inflammatory compound.

Registry Numbers and Inventories.
CAS
22071-15-4
EC (EINECS/ELINCS)
244-759-8
23/24/25 36/37/38
26 36/37/39 45
RTECS
UE7570000
RTECS class
Drug; Mutagen; Reproductive Effector; Human Data
UN (DOT)
2811
Merck
12,5316
Beilstein/Gmelin
2216071
Beilstein Reference
6-10
Canada DSL/NDSL
NDSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C16H14O3
Formula mass
254.29
Melting point, °C
95 - 96
Boiling point, °C
431
Vapor pressure, mmHg
3E-9 (25 C)
Density
1.16 g/cm3 (20 C)
Solubility in water
85 mg/L (22.5 C)
pKa/pKb
4.23 (pKa)
Partition coefficient, pKow
2.77
Heat of vaporization
72.4 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
229
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
0
 
 
Reactivity
1
 

Health.
Exposure effects
Toxic. Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Photosensitizer. Target organ(s): Kidneys. Liver.
   Ingestion
Toxic if swallowed.
   Inhalation
Toxic if inhaled. Material is irritating to mucous membranes and upper respiratory tract.
   Skin
Causes skin irritation. Toxic if absorbed through skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
III