(+-)-Kynurenine

  • a-2-Diamino-g-oxobenzenebutyric acid
  • 3-Anthraniloylalanine
Formula
C10H12N2O3
Structure
Uses
Substance is used in biochemical investigations.

Registry Numbers and Inventories.
CAS
343-65-7
EC (EINECS/ELINCS)
206-445-9
Merck
12,5340
Beilstein/Gmelin
2697333
Beilstein Reference
4-14-00-02562

Properties.
Formula
C10H12N2O3
Formula mass
208.22
Melting point, °C
191
Boiling point, °C
467
Vapor pressure, mmHg
1.7E-9 (25 C)
Density
1.34 g/cm3
Solubility in water
Insoluble
pKa/pKb
2.21 (pKa)
Partition coefficient, pKow
1.09
Heat of vaporization
76.74

Hazards and Protection.
Storage
Store in a cool, dry location. Avoid exposure to air or moisture.
Protection
Safety glasses with side-shields. PVC or other plastic material gloves. Usual safety precautions while handling the product will provide adequate protection against this potential effect.
Respirators
Breathing apparatus only if aerosol or dust is formed.
Small spills/leaks
Sweep up and shovel into suitable containers for disposal. Prevent product from entering drains.
Stability
Stable under recommended storage conditions.
Incompatibilities
Oxidizing and spontaneously flammable materials.
Decomposition
Nitrogen oxides (NOx)/ammonia/CN-

Fire.
Flash Point,°C
236
Fire fighting
Use dry chemical, CO2, water spray or alcohol foam. Water mist may be used to cool closed containers. As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
Combustion products
Burning produces irritant fumes.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
May include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, vomiting, headache. Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness.
   Ingestion
May be harmful if swallowed.
   Inhalation
May cause irritation of respiratory tract.
   Skin
May cause allergic skin reaction.
   Eyes
Avoid contact with eyes.

First aid
 
   Ingestion
Do not induce vomiting without medical advice.
   Inhalation
Move to fresh air. Call a physician immediately.
   Skin
Rinse immediately with plenty of water and seek medical advice.
   Eyes
In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Transport.