(L)-Aspartic acid

  • aminosuccinic acid
  • l-aminosuccinic acid
  • Asparagic acid
  • L-Asparagic acid
  • Asparaginic acid
  • L-Asparaginic acid
Formula
C4H7NO4
Structure
Description
Colorless crystals.
Uses
Biological & clinical studies, preparation of culture media, organic intermediate, ingredient of aspartame, detergents, fungicides, germicides, metal complexation aspartic acid.

Registry Numbers and Inventories.
CAS
56-84-8
EC (EINECS/ELINCS)
200-291-6
S 22 24/25
RTECS
CI9098500
RTECS class
Drug; Mutagen
Merck
13,845
Beilstein/Gmelin
1723530
Beilstein Reference
4-04-00-02998
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4H7NO4
Formula mass
133.10
Melting point, °C
251
Boiling point, °C
311
Decomposition point, °C
268 - 269
Vapor pressure, mmHg
0.003 (25 C)
Critical temperature
509
Critical pressure
53.5
Density
1.6613 g/cm3 (13 C)
Solubility in water
Very soluble
pKa/pKb
2.28 (pKa)
Partition coefficient, pKow
-3.89
Heat of combustion
-1583 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Keep from contact with oxidizing materials. Keep away from direct light.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong alkalies, strong acids and strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Laboratory experiments have resulted in mutagenic effects.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2922 49 95