L-Leucine

  • 2-Amino-4-methylpentanoic acid
  • (S)-2-Amino-4-methylvaleric acid
  • L-Norvaline, 4-methyl-
  • Pentanoic acid, 2-amino-4-methyl-, (S)-
  • L-a-Aminoisocaproic acid
Formula
C6H13NO2
Structure
Description
white solid. Practically odorless
Uses
Nutrient.

Registry Numbers and Inventories.
CAS
61-90-5
EC (EINECS/ELINCS)
200-522-0
RTECS
OH2850000
RTECS class
Mutagen; Reproductive Effector
Merck
13,5470
Beilstein/Gmelin
1721722
Beilstein Reference
4-04-00-02738
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C6H13NO2
Formula mass
131.18
Melting point, °C
300
Boiling point, °C
sublimes
Density
1.165 g/cm3
Solubility in water
Very soluble
pKa/pKb
2.55 (pKa)
Partition coefficient, pKow
-1.68

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective gloves to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.
Disposal code
31
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.

Health.
Exposure effects
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation. No information regarding eye irritation and other potential effects was found.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear.
   Skin
Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2922 49 95