L-(+)-Pseudoephedrine hydrochloride

  • d-(1S,2S)-Pseudoephedrine hydrochloride
  • d-[a-(1-Methylamino)ethyl]benzyl alcohol hydrochloride
  • Benzenemethanol, a-[(1S)-1-(methylamino)ethyl]-, hydrochloride, (aS)-
  • Sudafed
  • Novafed
Formula
C10H15NO.HCl
Structure
Description
White crystalline powder.
Uses
Medication.

Registry Numbers and Inventories.
CAS
345-78-8
EC (EINECS/ELINCS)
206-462-1
RTECS
UL5950000
RTECS class
Drug; Human Data
Beilstein/Gmelin
3915112
Beilstein Reference
4-13-00-01878
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C10H15NO*ClH
Formula mass
201.69
Melting point, °C
183 - 186
Density
1.198 g/cm3
Heat of fusion
28.0 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place.
Handling
Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Light, strong oxidizing agents.
Decomposition
Carbon dioxide and carbon monoxide, hydrogen chloride gas, nitrogen oxides, various hydrocarbons.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use extinguishing media most appropriate for the surrounding fire.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability. Prolonged exposure may cause mental changes such as hallucinations, depression, psychosis, and possibly coma. Repeated or prolonged exposure may cause CNS stimulation.
   Ingestion
May cause irritation of the digestive tract. May be harmful if swallowed. May cause central nervous system effects and/or neurological effects.
   Inhalation
The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.