L-Tyrosine

  • 3-(4-Hydroxyphenyl)-L-alanine
Formula
C9H11NO3
Structure
Description
Fine silky needles.
Uses
Nutrient &or dietary supplement.

Registry Numbers and Inventories.
CAS
60-18-4
EC (EINECS/ELINCS)
200-460-4
R 36/37/38
RTECS
YP2275600
RTECS class
Mutagen; Reproductive Effector
Merck
12,9970
Beilstein/Gmelin
392441
Beilstein Reference
4-14-00-02264
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C9H11NO3
Formula mass
181.19
Melting point, °C
285
Boiling point, °C
351
Decomposition point, °C
295 - 298
Vapor pressure, mmHg
1E-6 (25 C)
Vapor density (air=1)
1.456
Evaporization number
0 (butyl acetate=1)
Critical temperature
559
Critical pressure
47.1
Density
1.41 g/cm3
Solubility in water
Very soluble
Viscosity
1.33 cp (34 C)
pKa/pKb
2.25 (pKa)
Partition coefficient, pKow
0.39
Heat of combustion
-4485 kJ/mol

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
176
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Health.
Exposure effects
Reproductive effects have been reported in animals.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
May cause skin irritation. The toxicological properties of this material have not been fully investigated.
   Eyes
Contact may cause transient eye irritation. The toxicological properties of this material have not been fully investigated.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Transport.
HS Code
2922 50 00