L-tert-Leucine

  • 3--Methyl-L-valine
  • (2S)-2-Amino-3,3-dimethylbutanoic acid
  • L-tert-Butylglycine
  • L-Pseudoleucine
  • L-2-Amino-3,3-dimethylbutyric acid
Formula
(CH3)3CCH(NH2)COOH
Structure
Description
Solid.

Registry Numbers and Inventories.
CAS
20859-02-3
S 22 24/25
Beilstein/Gmelin
1721824
Beilstein Reference
4-04-00-02785
New Zealand
Listed

Properties.
Formula
C6H13NO2
Formula mass
131.18
Melting point, °C
> 300
Solubility in water
Very soluble
pKa/pKb
2.39 (pKa)
Partition coefficient, pKow
0.53

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.
Disposal code
3
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.

Health.
Exposure effects
Prolonged or repeated exposure may cause adverse reproductive effects. May cause fetal effects.
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
The toxicological properties of this substance have not been fully investigated. Inhalation of dust may cause respiratory tract irritation.
   Skin
Low hazard for usual industrial handling.
   Eyes
No information regarding eye irritation and other potential effects was found. Contact may cause transient eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2922 49 95