loxapine

  • Cloxazepine
  • Loxapin
  • Oxilapine
  • 2-Chloro-11-(4-methylpiperazino)dibenz[b,f][1,4]oxazepine
  • 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine
Formula
C18H18ClN3O
Structure
Uses
Used in the treatment of psychotic disorders and schizophrenia.

Registry Numbers and Inventories.
CAS
1977-10-2
EC (EINECS/ELINCS)
217-835-3
RTECS
HQ4025000
RTECS class
Drug; Reproductive Effector
Merck
12,5617
Beilstein/Gmelin
626753
Beilstein Reference
6-27
Japan ENCS (MITI)
Listed

Properties.
Formula
C18H18ClN3O
Formula mass
327.81
Melting point, °C
108 - 111
Boiling point, °C
459
Vapor pressure, mmHg
1E-8 (25 C)
Solubility in water
12.5 mg/L (25 C)
pKa/pKb
7.72 (pKb)
Heat of vaporization
71.9 kJ/mol

Hazards and Protection.

Fire.
Flash Point,°C
231

Health.
Exposure effects
Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.

First aid
 

Transport.