- 4-Chloro-2-methylphenoxyacetic acid
- 4-Chloro-o-tolyloxyacetic acid
- (4-Chloro-2-methylphenoxy)acetic acid
Registry Numbers and Inventories.
EC Index Number
R 22 38 41
S 26 37 39
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant
Swiss Giftliste 1
Japan ENCS (MITI)
Melting point, °C
Boiling point, °C
Vapor pressure, mmHg
6E-6 (25 C)
Vapor density (air=1)
1.56 g/cm3 (25 C)
Solubility in water
Partition coefficient, pKow
Hazards and Protection.
Keep in well ventilated area.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Like 2,4-d self-contained breathing apparatus must be worn. Rubber gloves, hats, suits and boots must be worn.
Organic vapor acid gas canister is used.
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Reacts as a weak acid to neutralize bases, both organic (for example, the amines) and inorganic Reacts with cyanide salts in the presence of moisture to generate gaseous hydrogen cyanide May react if moist with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat Reacts in this way with all bases, both organic (for example, the amines) and inorganic Can react with active metals to form gaseous hydrogen and a metal salt Flammable and/or toxic gases and heat are generated by the reaction with with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.
When heated to decomposition it emits toxic fumes of hydrogen chloride and nitrogen oxides.
Self-contained breathing apparatus, rubber gloves, hats, suits and boots must be worn. Highly toxic fumes are imminent.
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Fire may produce irritating, corrosive and/or toxic gases.
Low dose exposures - vertigo, headache, malaise, and paresthesias may occur depending on the specific compound involved. High dose exposures - muscle twitching, spasms, profound weakness, polyneuritis, and unconsciousness may occur depending on the specific compound involved. Idiosyncratic reactions - peripheral neuropathies 2,4-D and 2,4,5-T have caused adverse reproductive effects in experimental animals. Allegations of human birth defects due to these compounds have not been confirmed.
Nausea, vomiting, and diarrhea have been reported. Necrosis of the gastrointestinal mucosa has been reported.
Ingestion of large amounts may cause bradypnea, respiratory failure, hyperventilation, or pulmonary edema.
Direct contact may cause skin irritation. Chlorodioxin contamination of products may produce chloracne with heavy exposure.
Eye, nose, and mouth irritation are possible with direct contact.
Seek medical assistance.
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.