Mebendazole

  • Methyl 5-benzoylbenzimidazol-2-ylcarbamate
  • Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester
  • Bantenol
  • Vermicidin
  • Equivurm Plus
  • Ovitelmin
Formula
C16H13N3O3
Structure
Description
White to slightly yellow powder. Pleasant taste.
Uses
Medication.

Registry Numbers and Inventories.
CAS
31431-39-7
EC (EINECS/ELINCS)
250-635-4
RTECS
EY8600000
RTECS class
Drug; Mutagen; Reproductive Effector
Merck
12,5807
Beilstein/Gmelin
688513
EPA OPP
600073
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C16H13N3O3
Formula mass
295.3
Melting point, °C
295 - 296
Solubility in water
Insoluble
pKa/pKb
8.99 (pKb)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.
Small spills/leaks
STORAGE PRECAUTIONS: You should store this material under ambient temperatures.
Stability
No data.
Incompatibilities
Incompatible with strong acids and bases, and especially

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is probably combustible.

Health.
Exposure effects
   Ingestion
See inhalation.
   Inhalation
Symptoms of exposure to this compound may include headache, dizziness, gastrointestinal disturbances, pruritus, drowsiness, abnormalities in liver-function test, eosinophilia, lowered hemoglobin concentrations, leucopenia, hematuria and casts, cough, fever, glomerulonephritis, abdominal pain, diarrhea, nausea and vomiting. It may also cause allergic reactions, alopecia and reversible neutropenia.
   Skin
See inhalation.
   Eyes
See inhalation

First aid
 
   Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. If symptoms (such as redness or irritation) develop, immediately transport the victim to a hospital.

Transport.