Mechlorethamine hydrochloride

  • N-Methylbis(2-chloroethyl)amine hydrochloride
Formula
C5H11Cl2N . HCl
Structure
Description
White to off-white crystals or powder with a fishy odor.

Registry Numbers and Inventories.
CAS
55-86-7
EC (EINECS/ELINCS)
200-246-0
RTECS
IA2100000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
UN (DOT)
1693
Beilstein/Gmelin
605323
Beilstein Reference
4-04-00-00446

Properties.
Formula
C5H11Cl2N.ClH
Formula mass
192.52
Melting point, °C
-60
Boiling point, °C
87 (18 torr)
Density
1.118 g/cm3 (25 C)
Solubility in water
Soluble
Refractive index
1.4689 (24 C)

Hazards and Protection.
Storage
Poison room locked.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
Respirators
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks
Sweep up, then place into a suitable container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents - moisture.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Fire fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.
Fire potential
This material is probably combustible.
Hazards
Containers may explode when heated.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.

Health.
Exposure limit(s)
OSHA: Possible Select carcinogen
Carcinogin
N-2, CP65
Exposure effects
The toxological properties of this substance have not been fully investigated.
   Inhalation
Inhalation of vapors or dust is extremely irritating. May cause coughing, difficult breathing and nausea. Brief exposure effects last only a few minutes. Exposure in an enclosed area may be very harmful.
   Eyes
May cause burning of eyes and flow of tears.

First aid
 
   Ingestion
Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.
UN number
1693
Response guide
Hazard class
6.1
Packing Group
II