- 2-(4-Chloro-o-tolyloxy)propionic acid
- 2-(4-Chloro-2-methylphenoxy)propanoic acid
Selective herbicide for post-emergence control of broad-leaved weeds in wheat, barley, oats, herbage seed crops, grassland, and under fruit trees and vines, and control of docks in meadow and pastures.
Registry Numbers and Inventories.
EC Index Number
R 22 38 41
S 26 37/39
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector
Swiss Giftliste 1
Melting point, °C
92 - 94
Boiling point, °C
Vapor density (air=1)
Solubility in water
Partition coefficient, pKow
Hazards and Protection.
Do not store near heat or open flame. Protect from freezing. Storage site should be close to lab so that only small quantities required for experimentation need to be carried. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Dispensers of liquid detergent should be available. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, and disposable plastic aprons might provide additional protection. Protective clothing should be of distinctive color, as a reminder not to be worn outside the laboratory.
Wear positive pressure self-contained breathing apparatus (SCBA).
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
It is stable to heat and resistant to redn, hydrolysis, atmospheric oxidn. Solutions of the salt of mcpp are stable for several yr under normal storage conditions. At low temperatures the salt will crystallize out of solution, but the crystals will redissolve on warming. Salts of mecoprop.
Strong oxidizing agents.
May give off chlorine compounds and carbon monoxide.
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Water spray, fog or regular foam.
Pure mecoprop as well as commercial products are nonflammable.
Containers may explode when heated.
Fire may produce irritating, corrosive and/or toxic gases.
Low dose exposures - vertigo, headache, malaise, and paresthesias may occur depending on the specific compound involved. High dose exposures - muscle twitching, spasms, profound weakness, polyneuritis, and unconsciousness may occur depending on the specific compound involved. Idiosyncratic reactions - peripheral neuropathies 2,4-D and 2,4,5-T have caused adverse reproductive effects in experimental animals. Allegations of human birth defects due to these compounds have not been confirmed.
Nausea, vomiting, and diarrhea have been reported. Necrosis of the gastrointestinal mucosa has been reported.
Ingestion of large amounts may cause bradypnea, respiratory failure, hyperventilation, or pulmonary edema.
Direct contact may cause skin irritation. Chlorodioxin contamination of products may produce chloracne with heavy exposure.
Eye, nose, and mouth irritation are possible with direct contact.
Induce vomiting with Ipecac syrup. Seek medical advice.
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.