Medroxyprogesterone

  • 6-Dihydromegestrol
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-alpha-methyl
  • 6-alpha-Methyl-17-alpha-hydroxyprogesterone
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6-alpha)- (9CI)
  • U-8840
Formula
C22H32O3
Structure
Description
Odorless, off-white crystalline powder.
Uses
Contraceptive.

Registry Numbers and Inventories.
CAS
520-85-4
EC (EINECS/ELINCS)
208-298-6
48 63 68
22 24/25
RTECS
TU5300000
RTECS class
Reproductive Effector; Human Data; Hormone
Merck
12,5838
Beilstein/Gmelin
2510965
Beilstein Reference
4-08-00-02211

Properties.
Formula
C22H32O3
Formula mass
344.49
Melting point, °C
220
Boiling point, °C
488
Vapor pressure, mmHg
1E-11 (25 C)
Solubility in water
Insoluble
pKa/pKb
13.04 (pKa)
Heat of vaporization
86.9 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide.

Fire.
Flash Point,°C
263
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
0
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.
   Ingestion
May be harmful if swallowed.
   Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.