Menadione

  • aquakay
  • aquinone
  • Hemodal
  • Kaergona
  • Kanone
  • Kappaxan
Formula
C11H8O2
Structure
Description
Bright yellow crystals. Very faint acrid odor.
Uses
Prothrombogenic vit, vet: in hypoprothrombinemia & bishydroxycourmarin poisoning, incl sweet clover poisoning.

Registry Numbers and Inventories.
CAS
58-27-5
EC (EINECS/ELINCS)
200-372-6
R 22 36/37/38
S 26 36/37/39
RTECS
QL9100000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector
UN (DOT)
1325
Merck
13,5853
Beilstein/Gmelin
1908453
Beilstein Reference
4-07-00-02430
EPA OPP
6319
Swiss Giftliste 1
G-5338
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C11H8O2
Formula mass
172.18
Melting point, °C
103 - 105
Boiling point, °C
305
Vapor pressure, mmHg
0.0009 (25 C)
Density
1.26 - 1.35 g/cm3 (14 - 25 C)
Solubility in water
0.16 g/L at 30 C
Refractive index
1.4938 (20 C)
Partition coefficient, pKow
2.20
Heat of vaporization
54.5 kJ/mol
Heat of combustion
-5242 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Stability
Stable under normal temperatures and pressures. May decompose when exposed to light.
Incompatibilities
Stron oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C
114
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.
Fire potential
Flammable/combustible material. May be ignited by friction, heat, sparks or flames.
Combustion products
Fire may produce irritating and/or toxic gases.

Health.
Poison_Class
4
Exposure effects
Abnormally low blood pressure may occur precipitously following intravenous injection of phytonadione. Seizures have been rarely reported following intravenous phytonadione injection.
   Ingestion
Harmful if swallowed. The toxicological properties of this substance have not been fully investigated.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1325
Response guide
Hazard class
4.1
Packing Group
II; III